Lichen planus treatment aims to relieve symptoms—primarily itching and inflammation—and promote lesion healing, though there is no definitive cure.
First-line treatments for cutaneous lichen planus typically start with high‑potency topical corticosteroids such as clobetasol applied twice daily for 2–4 weeks. Intralesional steroid injections (e.g., triamcinolone) are used for resistant or hypertrophic lesions
NCBI
PMC
PubMed
For widespread, severe, or recalcitrant disease, systemic options include oral corticosteroids (e.g., prednisone 30–60 mg with tapering)
NCBI
AAFP
, as well as systemic retinoids (acitretin or isotretinoin) and immunosuppressants such as cyclosporine
PMC
Yale Medicine
Adjunct treatments for persistent or diffuse cases may include phototherapy, such as PUVA (psoralen + UVA) or narrow-band UVB, often in combination with retinoids
AAFP
PMC
PubMed
If initial treatments fail, second-line agents like metronidazole, sulfasalazine, hydroxychloroquine, methotrexate, azathioprine, mycophenolate mofetil, and even biologics may be considered
NCB
LUSH SKIN & HAIR CLINIC WE TREAT LICHEN PLANUS TREATMENT IN BEST WAY IN SHAHEEN BAGH, ABUL FAZAL, JAMIA NAGAR , SARITA VIHAR, OKHLA VIHAR , JASOLA& KHADA COLONY.